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Brain fitness
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From: AOLnews

Robert Stock

A week before the world economic summit got under way in Davos, Switzerland, last month, a self-proclaimed "global summit" of a very different sort was winding down. Its 250 or so participants from 15 countries were meeting in cyberspace –- and their topic had more to do with what goes on in your head than with economics, though there was plenty of that as well.


In the last few years, there has been a surge of interest -– by scientists and by entrepreneurs –- in brain fitness.

Both parties were well represented at the online summit. They share a burning desire to understand why and how we suffer memory loss as we age and what can be done about it.

We used to assume that forgetfulness was just another inevitable byproduct of aging, something to be accepted with a shrug and a laugh.

What could be funnier than Grandpa's forgetting he already locked the barn door? On the other hand, what could be more upsetting for Grandpa, and for the rest of us ancients who are constantly forgetting friends' names and where we left our glasses? Next stop, dementia?

Then researchers discovered that even in later years the normal brain retains its plasticity, its capacity to change and build new connections among cells. Suddenly it seemed possible to combat memory loss the same way we combat physical decline – by exercising. New, really challenging games and activities might actually rebuild our mental muscles, including reasoning, speed of processing and attention, as well as memory.


Enter the entrepreneurs. A huge market beckoned: The 78 million baby boomers were entering the age of forgetfulness. In 2008, sales of brain-fitness software hit $265 million. The industry expects that number to reach at least $1 billion within five years.

Meanwhile, anything and everything that could possibly enhance our brain fitness was being tested or ballyhooed.

Last year, for example, ginkgo was ruled out, but blueberries, grape juice and specific sounds played during deep sleep were in. Studies have shown that diets devoted to a healthy heart – little sugar, much fish – are especially good for brain function, as is regular aerobic exercise.

The pioneer in the development of brain-fitness software is San Francisco-based Posit Science, whose founders include a pioneering neuroscientist, Dr. Michael Merzenich.

positscience.com
This screen grab shows "Word Wanderer," one of the online "Brain Games" offered by Posit Science.
Merzenich created the Brain Fitness Program. It takes the user through a series of six basic exercises of ever-increasing difficulty, aimed at improving the brain's ability to process sounds and strengthen short-term memory of things like names and elusive words. The company's second product, Insight, uses visual exercises to increase the brain's ability to process and recall what is seen.

There have been all sorts of studies to determine the effectiveness of brain-fitness software. In one major study, a group of elders was given cognitive tests after completing the Brain Fitness Program. Elizabeth Zelinski, a professor at the University of Southern California Davis School of Gerontology, who was one of the study's authors, summarized the results: "People in their 70s using the Posit Science software had scores comparable to those of people in their 60s who had not completed the program."

That shows up as "improves memory by the equivalent of 10 years" on the Posit Science Web site.

Zelinski emphasized the limits of the study. "The principles of brain plasticity training work, but for healthy, motivated adults," she said. "The study does not show it works for people with serious cognitive impairments. We don't know how long the benefits will last or whether booster training would help in that regard. We don't know whether the benefits come from the whole program or some particular part of it."

Posit Science is far from alone in the brain-fitness business. Nintendo offers a hand-held device with all sorts of games to exercise the mind, as does Dakim's elaborate touch-screen computer console. Both emphasize how much fun their programs provide. That's because anything that can really boost old folks' memories is hard work.

I speak from experience. I've tried.

The way I've been losing chunks of my memory reminds me of the Dance of the Seven Veils, but in reverse. You start out having trouble remembering something like a phone number and then, over time, one layer of mist after another rises into place between you and the information stored in your brain.

No, the doctor says, it's not Alzheimer's – you're just getting a little senile.

Senile? Who, me?

I could have registered to learn a new language or taken up the piano. Instead, I signed up for Posit Science's Brain Fitness program for (gasp!) $395. It seemed to have the strongest scientific backing.

For a few weeks I went at it hammer and tongs, an hour a day -– distinguishing one sound from another, trying to remember a series of verbal instructions to move icons around a make-believe city street. Pretty soon that hour a day shrank to 30 minutes every other day.

Have all those exercises worked their magic? Truth to tell, I simply don't know. I stopped signing on to the program months ago.

Why? Partly because I have more work, so less spare time. But there's another reason, which you've probably already guessed. Yup, I keep forgetting to do it.
Filed under: Nation, Science, Health





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The Riddle of Consciousness

February 7th 2010 20:23
Consciousness
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From: The New York Times



By BENEDICT CAREY
Published: February 5, 2010

The assorted mystics, philosophers, theologians and, most recently, neuroscientists who have burned a candle searching for the essence of consciousness all started with a simple presumption: Consciousness must begin where unconsciousness ends.

Theologians have likened this state of pre-awakening to sleep, to darkness, to life underground. Modern scientists study the neural processes of sleep itself, and the transition to waking; they also have analyzed what happens in the brain when people suddenly become consciously aware of an object that was hidden in plain sight.

So far, the precise neural correlates of consciousness — the brain circuits critical to “turning on” conscious awareness — have eluded capture.

One reason is that consciousness itself takes many forms, from the gauzy half-dream state between the alarm clock’s bleating and sitting up; and lost stretches of waking life, as when a driver pulls into the driveway with no recollection of the half-hour commute home.

The deeper that investigators dig, the more hidden chambers they find. Last Wednesday, scientists in England and Belgium reported that five people with severe brain injuries who had been identified as “vegetative,” beyond reach, showed activity on brain imaging that strongly suggested conscious awareness. One of them, a 29-year-old man thought to be “vegetative” for five years, began to answer yes and no questions by alternately showing brain activity when thinking about tennis (lighting motor areas), then about walking in his house (lighting spatial areas).

A locked door on consciousness had swung open, all right; but on the other side was yet another dark corridor. After five years of being in effect buried alive in its own skull, what kind of consciousness was left for this patient? Who, exactly, lives behind those blank eyes? And, for that matter, what name do we give to this conscious state that looks totally absent, except for the ghostly blinking pixels on a brain imaging machine?

In the study, numerous severely injured patients classified as minimally conscious — that is, who intermittently are able to respond to commands — did not show meaningful activity on brain scans at all when prompted. Are those who did show flares of activity more conscious than they are?

“This scanning technology will allow us to refine diagnosis,” said Dr. Joseph Fins, chief of the medical ethics division of New York-Presbyterian Hospital/Weill Cornell hospital, “but it also creates this never-never land, these paradoxes between what patients are demonstrating clinically and what they manifest on the images.”

He added, “You know the person is there, you just don’t know how much is still there.”

Or how what’s there relates to what we call waking consciousness. Findings from modern neuroscience suggest that the brain is a highly social organ; more than enjoying company, it needs interactions to develop, to regulate mood, to solve problems, to responds to threats. When people are in isolation their brainwaves slow down; prisoners can become withdrawn, traumatized. The people out there who have been misidentified as being “vegetative” suffer a kind of solitary confinement unknown to prisoners of war. Their conscious awareness — especially in light of damaged cells in the brain — may be highly variable through the day and distinct from patient to patient.

Before doctors learn how it is that the brain’s lights turn on, they may have to know a lot more about what’s happening when the lights are off.







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February 6th 2010 23:42
Human body facts video
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